Table 1 Demographic and clinical characteristics of CADASIL patients and controls

Male/Female

13/9

26/18

1

Age at visit (years), mean ± SD

48.9 ± 14.2

48.4 ± 13.7

0.890

Age at first symptom (years), mean ± SD

44.6 ± 12.4

–

–

Family history, n (%)

20 (90.9)

–

–

Previous stroke or TIA (times), mean ± SD

2.0 ± 2.3

–

–

Headache, n (%)

4 (18.2)

–

–

Vascular disease risk factors, n (%)

11 (50.0)

–

–

MMSE score, mean ± SD

23.5 ± 5.7

28.2 ± 1.3

0.001

MoCA score, mean ± SD

20.4 ± 7.6

27.8 ± 1.3

0.000

NIHSS score, mean ± SD

1.4 ± 2.1

–

–

mRs score, mean ± SD

1.5 ± 1.2

–

–

HAMD score, mean ± SD

6.8 ± 6.4

3.9 ± 1.7

0.052

HAMA score, mean ± SD

5.7 ± 5.4

3.8 ± 1.7

0.112