Structural changes of cerebellum and brainstem in migraine without aura

Table 4 Clinical correlations with altered GMVs and diffusion characteristics of patients with MWoA.

	Disease duration (years)	Duration (hours)	Frequency (times/ months)	Pain intensity VAS	MIDAS	HIT-6
Decreased GMVs at SpV
r	0.119	0.169	-0.249	0.044	-0.221	0.038
P value	0.432	0.261	0.096	0.773	0.140	0.800
Decreased FA at Vermis VI extending to the bilateral lobule V and bilateral lobule VI
r	-0.047	-0.250	0.347	0.006	0.190	0.110
P value	0.759	0.094	0.018	0.970	0.206	0.465
Increased AD at R-ICP
r	-0.058	-0.125	0.160	0.218	0.106	0.120
P value	0.703	0.407	0.289	0.146	0.485	0.425
increased MD at R-ICP
r	-0.105	-0.072	0.139	0.147	0.064	0.050
P value	0.486	0.633	0.355	0.330	0.671	0.741
increased RD at R-ICP
r	-0.155	-0.051	0.123	0.114	0.065	0.033
P value	0.305	0.734	0.416	0.449	0.670	0.827
increased AD at SpV
r	-0.246	0.034	0.107	-0.023	-0.050	-0.135
P value	0.099	0.823	0.479	0.881	0.740	0.370
increased MD at SpV
r	-0.234	0.053	0.105	-0.036	-0.038	-0.165
P value	0.118	0.728	0.486	0.814	0.803	0.273
increased RD at SpV
r	-0.250	0.087	0.106	-0.044	-0.041	-0.162
P value	0.094	0.566	0.482	0.770	0.786	0.283

VAS Visual analogue scale, MIDAS Migraine disability assessment scale, HIT-6 Headache impact test; Frequency: the average number of attacks per month in the last three month; AD Axial diffusivity, MD Mean diffusivity, RD Radial diffusivity, FA Fractional anisotropy, SCP Superior cerebellar peduncle, MCP Middle cerebellar peduncle, ICP Inferior cerebellar peduncle, SpV Spinal trigeminal nucleus, r Spearson’s rho; Significant correlations were determined according to p<0.0083 (Bonferroni corrected for multiple comparisons, p<0.05).

ISSN: 1129-2377