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Table 4 Clinical correlations with altered GMVs and diffusion characteristics of patients with MWoA.

From: Structural changes of cerebellum and brainstem in migraine without aura

  Disease duration (years) Duration (hours) Frequency (times/ months) Pain intensity VAS MIDAS HIT-6
Decreased GMVs at SpV
 r 0.119 0.169 -0.249 0.044 -0.221 0.038
 P value 0.432 0.261 0.096 0.773 0.140 0.800
Decreased FA at Vermis VI extending to the bilateral lobule V and bilateral lobule VI
 r -0.047 -0.250 0.347 0.006 0.190 0.110
 P value 0.759 0.094 0.018 0.970 0.206 0.465
Increased AD at R-ICP
 r -0.058 -0.125 0.160 0.218 0.106 0.120
 P value 0.703 0.407 0.289 0.146 0.485 0.425
increased MD at R-ICP
 r -0.105 -0.072 0.139 0.147 0.064 0.050
 P value 0.486 0.633 0.355 0.330 0.671 0.741
increased RD at R-ICP
 r -0.155 -0.051 0.123 0.114 0.065 0.033
 P value 0.305 0.734 0.416 0.449 0.670 0.827
increased AD at SpV
 r -0.246 0.034 0.107 -0.023 -0.050 -0.135
 P value 0.099 0.823 0.479 0.881 0.740 0.370
increased MD at SpV
 r -0.234 0.053 0.105 -0.036 -0.038 -0.165
 P value 0.118 0.728 0.486 0.814 0.803 0.273
increased RD at SpV
 r -0.250 0.087 0.106 -0.044 -0.041 -0.162
 P value 0.094 0.566 0.482 0.770 0.786 0.283
  1. VAS Visual analogue scale, MIDAS Migraine disability assessment scale, HIT-6 Headache impact test; Frequency: the average number of attacks per month in the last three month; AD Axial diffusivity, MD Mean diffusivity, RD Radial diffusivity, FA Fractional anisotropy, SCP Superior cerebellar peduncle, MCP Middle cerebellar peduncle, ICP Inferior cerebellar peduncle, SpV Spinal trigeminal nucleus, r Spearson’s rho; Significant correlations were determined according to p<0.0083 (Bonferroni corrected for multiple comparisons, p<0.05).