Structural changes of cerebellum and brainstem in migraine without aura

Table 3 Diffusion characteristics for 3 major cerebellar tracts in the MWoA and healthy controls.

	L-SCP	R-SCP	L-MCP	R-MCP	L-ICP	R-ICP
AD
HC	0.92±0.14	0.91±0.14	0.83±0.12	0.86±0.12	0.90±0.14	0.89±0.14
MWoA	0.94±0.10	0.96±0.10	0.81±0.08	0.84±0.08	0.96±0.10	0.97±0.11
P value	0.590	0.069	0.324	0.462	0.045	0.002*
MD
HC	0.63±0.11	0.62±0.10	0.57±0.14	0.59±0.13	0.70±0.12	0.69±0.11
MWoA	0.63±0.07	0.66±0.08	0.52±0.05	0.55±0.05	0.75±0.08	0.76±0.09
P value	0.997	0.072	0.032	0.044	0.057	0.001*
RD
HC	0.48±0.10	0.48±0.09	0.44±0.15	0.45±0.15	0.60±0.11	0.59±0.10
MWoA	0.47±0.06	0.51±0.07	0.38±0.04	0.40±0.04	0.64±0.07	0.65±0.08
P value	0.694	0.094	0.013	0.015	0.079	0.001*
FA
HC	0.30±0.06	0.30±0.05	0.37±0.12	0.37±0.12	0.22±0.05	0.21±0.05
MWoA	0.31±0.04	0.31±0.04	0.41±0.05	0.41±0.05	0.23±0.03	0.23±0.03
P value	0.157	0.162	0.012	0.011	0.094	0.125

AD Axial diffusivity, MD Mean diffusivity, RD Radial diffusivity, FA Fractional anisotropy, SCP Superior cerebellar peduncle, MCP Middle cerebellar peduncle, ICP Inferior cerebellar peduncle, * Statistical significance was set at p<0.0083, (Bonferroni corrected p<0.05). The MD, RD, and AD metrics are shown as 10^-3, and FA is shown as the actual value. Note that only the right inferior cerebellar peduncle displayed significant increases in MD, RD, and AD compared with controls.

ISSN: 1129-2377