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Table 4 Volumes (mean values with standard deviations in parenthesis) of white matter tracts with significant differences between various headache groups obtained via automated tractography. Only significant comparisons are shown

From: Diffusion tensor imaging in middle-aged headache sufferers in the general population: a cross-sectional population-based imaging study in the Nord-Trøndelag health study (HUNT-MRI)

White matter tract Diffusivity index Headache status Cohen’s d P-values
   Headache free TTH in HUNT3   
CC Model 1 133,199.55 (27,111.58) 128,233.64 (26,728.43) 0.18 0.015
Model 2 133,199.55 (27,111.58) 128,233.64 (26,728.43) 0.18 0.027
Model 3 133,333.22 (27,393.97) 128,279.36 (26,905.43) 0.19 0.013
Model 4 133,333.22 (27,393.97) 128,279.36 (26,905.43) 0.19 0.021
   Headache free Previous headache   
IFOF Model 3 55,877.84 (12,506.42) 52,031.05 (11,029.22) 0.33 0.044
Model 4 55,877.84 (12,506.42) 52,031.05 (11,029.22) 0.33 0.044
   Headache free New onset headache   
CC Model 1 133,199.55 (27,111.58) 123,362.10 (23,524.54) 0.39 0.001
Model 2 133,199.55 (27,111.58) 123,362.10 (23,524.54) 0.39 0.002
Model 3 133,333.22 (27,393.97) 123,476.03 (24,022.37) 0.38 0.003
Model 4 133,333.22 (27,393.97) 123,476.03 (24,022.37) 0.38 0.004
IFOF Model 1 55,849.15 (12,415.01) 52,573.81 (12,236.59) 0.27 0.013
Model 2 55,849.15 (12,415.01) 52,573.81 (12,236.59) 0.27 0.017
Model 3 55,877.84 (12,506.42) 52,797.27 (12,271.63) 0.25 0.014
Model 4 55,877.84 (12,506.42) 52,797.27 (12,271.63) 0.25 0.017
  1. Model 1 = Corrected for age, sex and ICV
  2. Model 2 = Corrected for age, sex, ICV and WMH
  3. Model 3 = Corrected for age, sex, ICV, HADS, chronic pain and consumption of alcohol and over-the-counter painkillers
  4. Model 4 = Corrected for age, sex, ICV, WMH, HADS, chronic pain and consumption of alcohol and over-the-counter painkillers
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