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Table 4 Volumes (mean values with standard deviations in parenthesis) of white matter tracts with significant differences between various headache groups obtained via automated tractography. Only significant comparisons are shown

From: Diffusion tensor imaging in middle-aged headache sufferers in the general population: a cross-sectional population-based imaging study in the Nord-Trøndelag health study (HUNT-MRI)

White matter tract

Diffusivity index

Headache status

Cohen’s d

P-values

  

Headache free

TTH in HUNT3

  

CC

Model 1

133,199.55 (27,111.58)

128,233.64 (26,728.43)

0.18

0.015

Model 2

133,199.55 (27,111.58)

128,233.64 (26,728.43)

0.18

0.027

Model 3

133,333.22 (27,393.97)

128,279.36 (26,905.43)

0.19

0.013

Model 4

133,333.22 (27,393.97)

128,279.36 (26,905.43)

0.19

0.021

  

Headache free

Previous headache

  

IFOF

Model 3

55,877.84 (12,506.42)

52,031.05 (11,029.22)

0.33

0.044

Model 4

55,877.84 (12,506.42)

52,031.05 (11,029.22)

0.33

0.044

  

Headache free

New onset headache

  

CC

Model 1

133,199.55 (27,111.58)

123,362.10 (23,524.54)

0.39

0.001

Model 2

133,199.55 (27,111.58)

123,362.10 (23,524.54)

0.39

0.002

Model 3

133,333.22 (27,393.97)

123,476.03 (24,022.37)

0.38

0.003

Model 4

133,333.22 (27,393.97)

123,476.03 (24,022.37)

0.38

0.004

IFOF

Model 1

55,849.15 (12,415.01)

52,573.81 (12,236.59)

0.27

0.013

Model 2

55,849.15 (12,415.01)

52,573.81 (12,236.59)

0.27

0.017

Model 3

55,877.84 (12,506.42)

52,797.27 (12,271.63)

0.25

0.014

Model 4

55,877.84 (12,506.42)

52,797.27 (12,271.63)

0.25

0.017

  1. Model 1 = Corrected for age, sex and ICV
  2. Model 2 = Corrected for age, sex, ICV and WMH
  3. Model 3 = Corrected for age, sex, ICV, HADS, chronic pain and consumption of alcohol and over-the-counter painkillers
  4. Model 4 = Corrected for age, sex, ICV, WMH, HADS, chronic pain and consumption of alcohol and over-the-counter painkillers