Fig. 1

Between group differences in white matter FA, MD, AD and RD in the TBSS analyses. Significance level was P < 0.05 (two-tailed) corrected for age and sex and multiple comparisons with Threshold Free Cluster Enhancement and Family-Wise Error rate as implemented in Randomise. To improve visualization, the group differences were “thickened” using the tbss_fill script in FSL. The FSL 1 mm mean FA template was used as background image