Table 3 One-year migraine improvement, in terms of modification in triptan use, among triptan-treated migraineurs with unmet medical needs (UMN) (both overall cohort and stratified for subtypes according to the average triptan dose units per month)
| Â | Total | Not Improved | Improveda | P value^ | ||
|---|---|---|---|---|---|---|
N | N | (%) | N | (%) | ||
Overall UMN migraineurs (≥ 4 triptan dose units) | 31,515 | 24,503 | (77.7) | 7012 | (22.3) |  |
 At least one oral preventive therapy in the 1st year | ||||||
  Yes | 6121 | 4913 | (80.3) | 1208 | (19.7) | <.01 |
  No | 25,394 | 19,590 | (77.1) | 5804 | (22.9) | |
 At least one botulinum toxin injection in the 1st year | ||||||
  Yes | 191 | 161 | (84.3) | 30 | (15.7) | .03 |
  No | 31,324 | 24,342 | (77.7) | 6982 | (22.3) | |
pLF-EM (4–9 triptan dose units) | 22,796 | 16,916 | (74.2) | 5880 | (25.8) |  |
 At least one oral preventive therapy in the 1st year | ||||||
  Yes | 3856 | 2944 | (76.3) | 912 | (23.7) | <.01 |
  No | 18,940 | 13,972 | (73.8) | 4968 | (26.2) | |
 At least one botulinum toxin injection in the 1st year | ||||||
  Yes | 71 | 46 | (64.8) | 25 | (35.2) | .07 |
  No | 22,725 | 16,870 | (74.2) | 5855 | (25.8) | |
pHF-EM (10–14 triptan dose units) | 5467 | 4725 | (86.4) | 742 | (13.6) |  |
 At least one oral preventive therapy in the 1st year | ||||||
  Yes | 1278 | 1125 | (88.0) | 153 | (12.0) | .06 |
  No | 4189 | 3600 | (85.9) | 589 | (14.1) | |
 At least one botulinum toxin injection in the 1st year | ||||||
  Yes | 49 | 48 | (98.0) | 1 | (2.0) |  |
  No | 5418 | 4677 | (86.3) | 741 | (13.7) | .02 |
pCM (> 14 triptan dose units) | 3252 | 2862 | (88.0) | 390 | (12.0) |  |
 At least one oral preventive therapy in the 1st year | ||||||
  Yes | 987 | 844 | (85.5) | 143 | (14.5) | <.01 |
  No | 2265 | 2018 | (89.1) | 247 | (10.9) | |
 At least one botulinum toxin injection in the 1st year | ||||||
  Yes | 71 | 67 | (94.4) | 4 | (5.6) | .10 |
  No | 3181 | 2795 | (87.9) | 386 | (12.1) | |