Fig. 4
From: Optimising migraine treatment: from drug-drug interactions to personalized medicine
Sumatriptan and Zolmitriptan metabolic profile. From left to right, in the first column there is the list of drug metabolizing enzymes, one for each row; in the second and third columns relationship between corresponding enzyme of the row and Sumatriptan (second column) and Zolmitriptan (third column): is indicated by the symbol ‘S’ for substrate. Enzyme CYP1A2 is rimmed to emphasize their importance in these triptans’ metabolic destiny. Related page at the website http://bioinformatics.charite.de/transformer