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Table 5 Plasma neurosteroid levels in the overall population of patients affected by chronic migraine during the headache attack and in the interictal period

From: Migraine and cluster headache show impaired neurosteroids patterns

 

Chronic migraine during attack (n = 27)

Chronic migraine

no attack (n = 24)

Controls

AP (ng/mL)

1.1 ± 0.4*

1.1 ± 0.2*

0.6 ± 0.3

EAP (ng/mL)

0.5 ± 0.1

0.4 ± 0.2

0.4 ± 0.1

DHEA (ng/mL)

1.4 ± 0.9*

1.8 ± 1.2*

5.1 ± 3.8

DHEAS (μg/mL)

1.5 ± 1.1*

1.0 ± 0.6*

2.7 ± 2.0

  1. Values are means + S.D. *p<0.05 vs. the respective control groups. No significant changes were found between values obtained during the attack and in the interictal period. Statistical analysis was performed by One-way ANOVA + Fisher’s LSD (AP, F2,79 = 24.79; EAP, F2,79 = 1.43; DHEA, F2,79 = 18.06; DHEAS, F2,79 = 10.66)
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The Journal of Headache and Pain

ISSN: 1129-2377

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