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Table 5 Plasma neurosteroid levels in the overall population of patients affected by chronic migraine during the headache attack and in the interictal period

From: Migraine and cluster headache show impaired neurosteroids patterns

  Chronic migraine during attack (n = 27) Chronic migraine
no attack (n = 24)
Controls
AP (ng/mL) 1.1 ± 0.4* 1.1 ± 0.2* 0.6 ± 0.3
EAP (ng/mL) 0.5 ± 0.1 0.4 ± 0.2 0.4 ± 0.1
DHEA (ng/mL) 1.4 ± 0.9* 1.8 ± 1.2* 5.1 ± 3.8
DHEAS (μg/mL) 1.5 ± 1.1* 1.0 ± 0.6* 2.7 ± 2.0
  1. Values are means + S.D. *p<0.05 vs. the respective control groups. No significant changes were found between values obtained during the attack and in the interictal period. Statistical analysis was performed by One-way ANOVA + Fisher’s LSD (AP, F2,79 = 24.79; EAP, F2,79 = 1.43; DHEA, F2,79 = 18.06; DHEAS, F2,79 = 10.66)
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