How to integrate monoclonal antibodies targeting the calcitonin gene-related peptide or its receptor in daily clinical practice

Table 1 Recommended dose regimens of CGRP MoAbs for migraine prevention

Drug	Route of administration	Dosage forms	Loading dose	Recommended dose regimen
Erenumab	sc injection	70 mg/mL solution	Not required	70 mg monthly^a
Fremanezumab	sc injection	225 mg/1.5 mL solution	Not required	225 mg monthly
Fremanezumab	sc injection	225 mg/1.5 mL solution	Not required	675 mg quarterly^b
Galcanezumab	sc injection	120 mg/mL solution	240 mg^c	120 mg monthly

^aTwo consecutive injections of 70 mg each may be reasonable for selected patients (see text)
^bThree consecutive injections of 225 mg each
^cTwo consecutive injections of 120 mg each

ISSN: 1129-2377