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Fig. 3 | The Journal of Headache and Pain

Fig. 3

From: Effects of monoclonal antagonist antibodies on calcitonin gene-related peptide receptor function and trafficking

Fig. 3

Colocalization of CGRP receptor subunits. AA58 (green) and RAMP1 (red) immunoreactivity co-localized (merged) with CLR-FAP fluorescence (magenta) as shown in a confocal optical slice of 0.15 μm with magnification 60x. Note the prominent membrane labeling by all three CGRP receptor detection agents. Additional, non-co-localized RAMP1 immunoreactivity (red) can be seen in the cytoplasm (merged), likely representing an artifact from overexpression. No immunoreactivity was observed in parental cells not expressing CGRP receptors (parental merged). Scale bar = 12 μm

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The Journal of Headache and Pain

ISSN: 1129-2377

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