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Table 2 Association between response to OnabotA and SNP rs3781719 in the gene CALCA

From: CALCA and TRPV1 genes polymorphisms are related to a good outcome in female chronic migraine patients treated with OnabotulinumtoxinA

     P value Odds ratio (95% CI)
POPULATION RESPONSE GENOTYPES MINOR ALLELE FREQUENCY (%) GENOTYPIC FREQUENCY ALLELE FREQUENCY ALLELE C RECESIVITY HYPOTHESIS ALLELE C DOMINANCE HYPOTHESIS Dominant model Codominant model Recessive model
TT TC CC
n = 150 Responders (n = 117) 63 45 9 26,9 0.023 0.029 0.794 0.007 3,11 (1,33-7,26) 1,6 (0,85-3,0) 1,2 (0,31-4,71)
Non-responders (n = 33) 9 21 3 40,9
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