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Table 3 Significant inter-group differences in the FC analysis of patients with CADASIL and controls

From: Relationship between changes in resting-state spontaneous brain activity and cognitive impairment in patients with CADASIL

Predominant regions in cluster Cluster size Peak T value MNI coordinates Cluster level PFWE-corr
    x y z  
CADASIL < controls (seed region: left SFG)
 Right precentral gyrus 116 −3.78 60 − 6 36 0.037
 Bilateral pons 115 −4.79 12 − 18 − 33 0.038
CADASIL < controls (seed region: right SFG)
 Right precentral gyrus 239 −4.14 48 9 39 0.001
 Left postcentral gyrus 133 − 4.48 − 51 − 21 39 0.020
CADASIL < controls (seed region: right Pcu/CU)
 Right cuneus 239 −5.42 6 −87 36 0.002
 Right PHG 184 − 5.35 24 −27 −3 0.007
CADASIL compared to controls (seed region: left cerebellar anterior and posterior lobes)
 Right pon 109 −4.93 9 −18 − 33 0.057
 Left cerebrum 31 −3.84 −24 −15 − 3 0.519
  1. The surviving clusters of FC were assigned thresholds at p < 0.001 and FWE-
  2. corrected to p < 0.05 at the cluster level
  3. FC functional connectivity, CADASIL cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy, SFG superior frontal gyrus, Pcu/CU precuneus and cuneus, PHG parahippocampal gyrus, MNI Montreal Neurological Institute
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