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Table 1 Demographic and clinical characteristics of the CADASIL and control groups

From: Relationship between changes in resting-state spontaneous brain activity and cognitive impairment in patients with CADASIL

  CADASIL group (n = 22) Control group (n = 44) p-values
Male/Female 13/9 26/18 1
Age at visit (years) 49.0 ± 14.2 48.5 ± 13.7 0.873
Family history, n (%) 19 (86.4) - -
Age at first symptom (years) 45.7 ± 13.3 - -
Previous stroke or TIA (times) 1.7 ± 2.7 - -
Vascular disease risk factors, n (%) 10 (45.5) - -
Headache, n (%) 3 (13.6) - -
Fazekas score 2.1 ± 1.2 - -
MMSE 23.3 ± 6.3 28.6 ± 1.1 0.001
MoCA 20.7 ± 7.9 27.9 ± 1.4 0.000
HAMD 7.0 ± 7.1 4.0 ± 1.8 0.067
HAMA 5.9 ± 6.0 3.7 ± 1.6 0.108
NIHSS 1.2 ± 1.9 - -
mRs 1.3 ± 1.2 - -
  1. Values are mean ± standard deviation (SD) or numbers and percentages. CADASIL cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy, MMSE Mini-Mental State Examination, MoCA Montreal Cognitive Assessment, HAMD Hamilton Depression Scale, HAMA Hamilton Anxiety Scale, NIHSS National Institute of Health Stroke Scale, mRs modified Rankin scale, SD standard deviation, TIA transient ischemic attack
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