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Table 3 Group differences in cortical thickness and volume

From: Influence of hemispheric white matter lesions and migraine characteristics on cortical thickness and volume

 

Groups

ANCOVA test

Lesion+

Lesion-

Control

Group effect

Age effect

ICV effect

F

P

F

P

F

P

Frontal thickness (mm)

2.51 (0.11)

2.55 (0.09)

2.51 (0.10)

1.41

0.246

63.12

< 0.001a

Parietal thickness (mm)

2.23 (0.11)

2.26 (0.11)

2.26 (0.11)

0.51

0.603

72.13

< 0.001a

Temporal thickness (mm)

2.81 (0.11)

2.83 (0.11)

2.80 (0.09)

0.92

0.401

35.91

< 0.001a

Occipital thickness (mm)

1.90 (0.10)

1.92 (0.09)

1.89 (0.08)

0.81

0.445

28.65

< 0.001a

Insula thickness (mm)

3.05 (0.14)

3.09 (0.14)

3.06 (0.12)

0.23

0.796

29.35

< 0.001a

Frontal volume (mm3)

158,308 (16892)

163,774 (15889)

161,019 (15212)

0.34

0.713

83.22

< 0.001a

92.04

< 0.001b

Parietal volume (mm3)

103,341 (11878)

106,370 (10566)

106,016 (8878)

0.11

0.897

70.13

< 0.001a

69.83

< 0.001b

Temporal volume (mm3)

98,752 (9514)

102,308 (8639)

100,105 (8294)

1.71

0.184

36.60

< 0.001a

78.76

< 0.001b

Occipital volume (mm3)

40,789 (5254)

42,196 (4531)

40,721 (4414)

1.23

0.294

33.85

< 0.001a

42.13

< 0.001b

Insula volume (mm3)

10,937 (1066)

11,039 (994)

10,938 (995)

0.28

0.758

24.25

< 0.001a

27.53

< 0.001b

  1. Lesion+: Migraine patients with lesions; Lesion-: Migraine patients without lesions; ICV: total intracranial volume; All thicknesses/volumes were excluded from the analysis, where the corresponding standardized residuals from the ANCOVA model were below −3 or above 3. Maximum three subjects had to be excluded from each group. Thicknesses and volumes are presented as uncorrected mean (standard deviation); anegative (inverse) association with thickness/volume, bpositive association with volume