Response rate | Galcanezumab 120 mg (N = 436) | Galcanezumab 240 mg (N = 428) | Placebo (N = 875) |
Episodic migrainea | |||
75% Response ≥3 consecutive monthsb | 19.7% | 21.3% | 8.5% |
Odds ratio (95% CI) | 2.7 (1.9, 3.7)* | 2.9 (2.1, 4.1)* | |
75% Response all 6 months | 6.2% | 6.8% | 1.8% |
Odds ratio (95% CI) | 3.5 (1.9, 6.3)* | 3.9 (2.1, 6.9)* | |
100% Response ≥3 consecutive monthsb | 3.7% | 6.5% | 2.7% |
Odds ratio (95% CI) | 1.4 (0.7, 2.5) | 2.5 (1.4, 4.2)* | |
100% Response all 6 months | 0.7% | 1.4% | 0.2% |
Odds ratio (95% CI) | 2.9 (0.8, 10.4) | 5.3 (1.6, 17.1)† | |
Chronic migrainec | Galcanezumab 120 mg (N = 273) | Galcanezumab 240 mg (N = 274) | Placebo (N = 538) |
30% Response all 3 months | 29.3% | 29.2% | 16.4% |
Odds ratio (95% CI) | 2.1 (1.5, 3.0)* | 2.1 (1.5, 3.1)* | |
75% Response all 3 months | 2.6% | 2.9% | 2.0% |
Odds ratio (95% CI) | 1.3 (0.6, 3.1) | 1.5 (0.6, 3.4) |