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Table 2 Parameters of the synaptic interface in each of the five groups in the TNC of CM rats

From: NR2B-Tyr phosphorylation regulates synaptic plasticity in central sensitization in a chronic migraine rat model

n = 6

Sham

CM

CM + DMSO

CM + PP2

CM + genistein

Thickness of the PSD/nm

22.24 ± 1.2321

40.51 ± 1.9948*

39.64 ± 1.5399*

25.34 ± 0.9563#

30.16 ± 0.6379#

Width of the synaptic cleft/nm

19.21 ± 0.8048

32.39 ± 0.4477*

32.37 ± 0.4968*

21.56 ± 0.9589#

22.63 ± 1.1490#

Active zones/nm

289.42 ± 8.31

529.8396 ± 18.6*

538.99 ± 23.15*

382.52 ± 23.51#

360.37 ± 22.64#

Synaptic interface curvature

1.080 ± 0.0202

1.331 ± 0.0284*

1.3115 ± 0.0184*

1.1643 ± 0.0156#

1.1357 ± 0.0125#

  1. n, the number of rats. Data are presented as the means ± SDs. *P < 0.05 compared with the sham control group. #P < 0.05 compared with the CM + DMSO control group