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Fig. 4 | The Journal of Headache and Pain

Fig. 4

From: NR2B-Tyr phosphorylation regulates synaptic plasticity in central sensitization in a chronic migraine rat model

Fig. 4

Expression of phosphorylated NR2B (pNR2B-Y1472 and pNR2B-Y1252) and tNR2B in each group. a The four rows show tNR2B, pNR2B-Y1472, pNR2B-Y1252 and β-actin. b The protein levels of pNR2B-Y1472 in the TNC were higher in the CM group than in the sham group. Compared with that found in the CM + DMSO group, PP2 and genistein significantly decreased the levels of pNR2B-Y1472. c The protein levels of pNR2B-Y1252 in the TNC were higher in the CM group than in the sham group. Compared with that found for the CM + DMSO group, PP2 and genistein significantly decreased the level of pNR2B-Y1252. d There was no significant difference in the expression of tNR2B among the different groups (n = 6 in each group, *P < 0.05 compared with the sham group, #P < 0.05 compared with the CM + DMSO group)

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