Fig. 1From: NR2B-Tyr phosphorylation regulates synaptic plasticity in central sensitization in a chronic migraine rat modelDevelopment of mechanical allodynia in rats. a The pain thresholds of the periorbital region were significantly decreased after three days of IS infusions compared with those detected after three days of PBS infusions. b A significant decrease in the hindpaw thresholds was observed after three days of IS infusions compared with those detected after three days of PBS infusions (n = 10 each group, *P < 0.01)Back to article page