Skip to main content

Table 1 Studies evaluating cognitive function in children with migraine

From: Cognitive dysfunction and migraine

Migraine Phase Cognitive Domains Affected in Migraine Study design Evaluation Methods Outcome Reference
Interictal Executive functions Cross sectional, clinic based Trail Making Test, Stroop Test Impairment in executive functions in children with migraine compared to healthy controls Costa-Silva et al., 2016 [31]
Interictal Attention Cross sectional, clinic based Trail Making Test, Test of Visual Attention Migraine group had difficulties in selective attention and mainly in alternate attention Villa et al., 2009 [32]
Interictal   Cross sectional, clinic based WISC-R Impairment in attention in children with migraine Moutran et al., 2011 [48]
Interictal   Cross sectional, clinic based Trail Making Test Impairment in selective and divided attention in children with migraine compared to control subjects Costa-Silva et al., 2016 [31]
Interictal Visuospatial memory Cross sectional, clinic based Rey Figure Test (Delayed recall) Delayed recall is impaired in children with migraine compared to controls D’Andrea et al., 1989 [33]
Interictal   Cross sectional, clinic based WISC-R Impairment in visuospatial memory in children with migraine Moutran et al., 2011 [48]
Interictal Verbal memory Cross sectional, clinic based Logical Memory Test, Ten Word Learning Test Memory is impaired in children with migraine compared to non-migrainous children D’Andrea et al., 1989 [33]
Interictal   Cross sectional, clinic based WISC-R Children with migraine performed worse than healthy controls Parisi et al., 2009 [34]
Interictal   Cross sectional, clinic based WISC-R Children with migraine had worse performance in verbal memory Moutran et al., 2011 [48]
Interictal   Cross sectional, clinic based Rey Auditory Verbal Learning Test Children with migraine perfomed significantly worse than control subjects Costa-Silva [31] et al., 2016
Interictal Information processing speed   Simple Visual Reaction Time Task A significant dysfunction was observed in the information processing rate in children with migraine Riva et al., 2006 [35]
Interictal   Cross sectional, clinic based WISC-R Children with migraine had decreased processing speed Moutran et al., 2011 [48]
Interictal   Cross sectional, clinic based Trail Making Test Children with migraine had slower information processing speed than controls Costa-Silva et al., 2016 [31]
Interictal Verbal skills Longitudinal, population based WISC-R Migraine patients were significantly impaired on tests of verbal ability between the ages 3 and 13 however no decline with age was observed Waldie et al., 2002 [30]
Interictal   Cross sectional, clinic based WISC-R Children with migraine had impaired verbal skills compared to healthy controls Parisi et al., 2009 [34]
Interictal   Cross sectional, clinic based Verbal Fluency Test Children with migraine displayed lower performance in the animals category Costa-Silva et al., 2016 [31]
Interictal Perceptual organization Cross sectional, clinic based WISC-R Perceptual organization was disturbed in children with migraine Moutran et al., 2011 [48]
Unspecified   Cross sectional, clinic based WISC-III Children with migraine had lower perceptual organization competence than children with tension-type headache or healthy controls Esposito et al., 2012 [36]
  1. WISC-R Wechsler Intelligence Scale for Children – Revised, WISC-III Wechsler Intelligence Scale for Children Third Edition