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Fig. 3 | The Journal of Headache and Pain

Fig. 3

From: Consistent effects of non-invasive vagus nerve stimulation (nVNS) for the acute treatment of migraine: additional findings from the randomized, sham-controlled, double-blind PRESTO trial

Fig. 3

Mean change in pain score from baseline for first attack during the double-blind (a) and open-label (b) periods and for all attacks during the double-blind (c) and open-label Periods (d). P values for first attack are from 2-sample t tests. For all attacks, linear mixed effects regression models were used to estimate the change in pain score between baseline and 30, 60, and 120 min, allowing for both subject-specific and population-averaged inferences. Abbreviations: CI, confidence interval; nVNS, non-invasive vagus nerve stimulation

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