Table 4 Efficacy of acute therapies in migraine and cluster headache

NSAIDs

Effective [155]

Not effective

Triptans

Oral route of administration

Subcutaneous sumatriptan/ intranasal sumatriptan or zolmitriptan [153, 154] effective

Inhalatory oxygen

Effective in about 46% of patients [156]

Effective: about two-third of patients [240]

Intranasal lidocaine

Conflicting data [159, 160]

Effective [125, 241]