Headache phenotype | Cluster Headache | Migraine without aura | Migraine with aura | |
---|---|---|---|---|
Location | Strictly unilateral | Usually unilateral | Similarities | |
Intensity | Severe/very severe | Moderate/severe | ||
Associated symptoms | Nausea, photophobia and phonophobia | |||
Aura (≈20%) [103] | - | Aura | ||
Quality | Excruciating, stabbing | Deep, pulsating | Differences | |
Duration | 15-180 minutes | 4-72 hours | ||
Radiation | Orbital, supraorbital and/or temporal | Frontotemporal | ||
Circadian/circannual rhythms | Nocturnal [22] Spring/autumn | Early morning [108]- | ||
Frequency | Once every other day to eight times a day | Once every other day | ||
Most common triggers | Alcohol [5] | Stress, cycling female hormones [239], [113] (but also alcohol) | ||
Aggravators | - | Routine physical activity | ||
Cranial autonomic symptoms | Ipsilateral, prominent | Bilateral, mild [66] | ||
Disability during headache | Restlessness or agitation | Severe impairment or require bed rest |