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Table 1 (abstract P22). Effect of erenumab in patients achieving ≥50% response in MMDs vs non-responders and overall population

From: 12th European Headache Federation Congress jointly with 32nd National Congress of the Italian Society for the Study of Headaches

Outcome measures

Erenumab 70 mg

Erenumab 140 mg

≥50% Responders

(N=75)

Non-responders

(N=113)

Overall population

(N=188)

≥50% Responders

(N = 77)

Non-responders

(N =110)

Overall population

(N=187)

Change from baseline to Week 12

 MMD

−12.2 (2.9)

−2.6 (4.3)

−6.6 (6.1)

−12.5 (4.6)

−2.2 (4.4)

−6.5 (6.8)

 MSMD

−5.2 (5.2)

−1.8 (4.1)

−3.3 (4.9)

−6.9 (5.6)

−2.4 (3.9)

−4.3 (5.2)

 HIT-6

−10.0 (7.6)

−2.8 (5.1)

−5.7 (7.2)

−10.7 (8.0)

−1.7 (5.1)

−5.5 (7.9)

 MIDAS total score

−29.1 (45.4)

−12.6 (41.5)

−19.5 (43.8)

−35.0 (45.2)

−5.8 (38.4)

−18.1 (43.7)

 MSQ-RFP

23.0 (19.4)

6.0 (19.8)

13.0 (21.3)

25.7 (23.2)

4.8 (16.2)

13.7 (22.1)

 MSQ-RFR

29.7 (18.6)

9.4 (19.8)

17.7 (21.7)

32.7 (23.7)

8.2 (18.5)

18.7 (24.1)

 MSQ-EF

30.5 (25.4)

11.1 (26.7)

19.1 (27.8)

33.3 (27.2)

6.3 (19.9)

17.8 (26.8)

  1. Data are expressed as mean (SD)
  2. HIT-6 Headache Impact Test (higher score indicates worse outcome), MIDAS Migraine Disability Assessment (higher score indicates worse outcomes), MMD monthly migraine days, MSQ Migraine-Specific Quality-of-Life Questionnaire (higher scores indicate better outcomes), MSQ-RFR Migraine-Specific Quality-of-Life Questionnaire role function-restrictive, MSQ-RFP Migraine-Specific Quality-of-Life Questionnaire role function-preventive, MSQ-EF Migraine-Specific Quality-of-Life Questionnaire emotional functioning, SD standard deviation