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Table 1 (abstract P21). Primary and secondary outcome measures in erenumab-treated responder and nonresponder subgroups in STRIVE

From: 12th European Headache Federation Congress jointly with 32nd National Congress of the Italian Society for the Study of Headaches

Erenumab 70 mg

Responders (n=135),

baseline

Responders,

change

Non responders (n=161), baseline

Non responders change

Overall

(n=312),

baseline

Overall,

change (mean±SE)

MMD

8.3 ±2.5

−6.1 ±2.1

8.3 ±2.4

−1.1 ±2.8

8.3 ±2.5

−3.4 ±0.2

MSMD

2.9 ±3.3

−2.0 ±2.4

3.8 ±3.5

−0.4 ±2.0

3.2 ±3.4

−1.1 ±0.1

MPFID-EA

13.5 ±8.5

−9.9 ±6.8

14.1 ±8.9

−2.4 ±7.0

14.0 ±8.9

−5.8 ±0.5

MPFID-PI

11.8 ±9.3

−8.4 ±7.00

12.7 ±9.6

−1.1 ±7.7

12.6 ±9.7

−4.4 ±0.5

Erenumab 140 mg

Responders (n=159),

baseline

Responders,

change

Non responders (n=143), baseline

Non responders change

Overall

(n=318),

baseline

Overall,

Change (mean±SE)

MMD

8.2 ±2.4

−6.0 ±2.1

8.5 ±2.5

−1.4 ±2.3

8.3 ±2.5

−3.8 ±0.2

MSMD

3.2 ±3.4

−2.3 ±2.6

3.6 ±3.5

−0.9 ±1.7

3.4 ±3.5

−1.6 ±0.1

MPFID-EA

12.6 ±7.9

−8.9 ±6.8

13.6 ±8.6

−2.5 ±7.0

13.0 ±8.2

−5.8 ±0.4

MPFID-PI

11.5 ±8.3

−7.6 ±7.0

12.8 ±9.7

−1.8 ±8.00

12.0 ±9.0

−4.8 ±0.5

  1. Data are mean ±standard deviation, except as indicated.
  2. MMD monthly migraine days, MSMD migraine-specific medication treatment days, MPFID-EA Migraine Physical Function Impact Diary domain scores for everyday activity, MPFID-PI MPFID-physical impairment, SE standard error