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Table 1 (abstract O36). Forward stepwise model* for the discrete time hazard to chronic migraine onset in comorbid classes of migraine in individuals with episodic migraine at baseline

From: 12th European Headache Federation Congress jointly with 32nd National Congress of the Italian Society for the Study of Headaches

  Hazard Ratio (95% CI)*
LCA Class Step 3 (Comorbid Class) Step 4 (Allodynia) Step 5 (Income ≥50k) Step 6 (Age) Step 7 (Gender) Step 8 (MSSS)
Most Comorbidities 2.80 (2.06, 3.80) 2.59 (1.91, 3.53) 2.49 (1.83, 3.39) 3.02 (2.17, 4.20) 3.07 (2.21, 4.27) 3.01 (2.17, 4.18)
Resp/Psych 1.86 (1.39, 2.47) 1.75 (1.31, 2.33) 1.75 (1.32, 2.34) 1.87 (1.40, 2.49) 1.93 (1.44, 2.58) 1.87 (1.40, 2.50)
Resp/Pain 2.25 (1.68, 3.02) 2.13 (1.59, 2.86) 2.21 (1.64, 2.96) 2.61 (1.91, 3.57) 2.63 (1.92, 3.60) 2.57 (1.88, 3.51)
Respiratory 1.40 (1.07, 1.82) 1.33 (1.01, 1.74) 1.35 (1.03, 1.76) 1.40 (1.07, 1.83) 1.42 (1.09, 1.87) 1.41 (1.07, 1.84)
Psych 2.22 (1.63, 3.03) 2.15 (1.58, 2.94) 2.10 (1.54, 2.87) 2.09 (1.53, 2.85) 2.12 (1.55, 2.89) 2.07 (1.52, 2.83)
Cardiovascular 1.21 (0.84, 1.74) 1.21 (0.84, 1.74) 1.25 (0.87, 1.80) 1.46 (1.00, 2.13) 1.40 (0.96, 2.04) 1.41 (0.96, 2.05)
Pain 1.35 (0.93, 1.97) 1.30 (0.89, 1.90) 1.32 (0.91, 1.93) 1.48 (1.01, 2.17) 1.42 (0.96, 2.09) 1.41 (0.96, 2.07)
  1. LCA latent class analysis, MSSS Migraine Symptom Severity Scale, Resp respiratory, Psych psychiatric
  2. *Step 1 added MIDAS and Step 2 added medication overuse and are not included in this table as the comorbid class only enters at Step 3.
  3. P≤0.05, compared with the “Fewest Comorbidities” class.
  4. P≤0.001, compared with the “Fewest Comorbidities” class