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Table 15 Drugs used by specialists in maintenance prophylaxis of cluster headache

From: Aids to management of headache disorders in primary care (2nd edition)

Verapamil 240–960 mg daily • ECG monitoring advised
Lithium carbonate 600–1600 mg daily • Serum levels must be regularly monitored
Topiramate 50–100 mg twice daily • Less evidence of efficacy, but no monitoring required