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Table 2 Brain regions showing significant main and interaction effects among four groups

From: Exploration of intrinsic brain activity in migraine with and without comorbid depression

  Region Hemi Voxel BA Peak voxel MNI coordinates T value
x y z
Main effect of migraine
 Cluster 1 PCC/Precuneus L/R 20 23 -3 −36 33 3.62
 Cluster 2 REC R 35 11 6 39 −18 −3.44
 Cluster 3 mPFC L 20 10 −36 45 9 4
Main effect of depression
 Cluster 1 mPFC L 752 10 −30 51 6 8.46
Interaction effect
 Cluster 1 Thalamus R 10 NA 12 −12 6 3.30
 Cluster 2 fusiform R 38 37 27 −3 −42 −4.07
  1. Hemi hemisphere, L left, R right, BA Brodmann Area, MNI Montreal Neurological Institute, x, y, z, coordinates of primary peak locations in the MNI space, T value statistical value of peak voxel showing ALFF differences among the four groups, PCC posterior cingulated cortex, REC rectus gyrus, mPFC medial prefrontal cortex