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Table 2 Brain regions showing significant main and interaction effects among four groups

From: Exploration of intrinsic brain activity in migraine with and without comorbid depression

 

Region

Hemi

Voxel

BA

Peak voxel MNI coordinates

T value

x

y

z

Main effect of migraine

 Cluster 1

PCC/Precuneus

L/R

20

23

-3

−36

33

3.62

 Cluster 2

REC

R

35

11

6

39

−18

−3.44

 Cluster 3

mPFC

L

20

10

−36

45

9

4

Main effect of depression

 Cluster 1

mPFC

L

752

10

−30

51

6

8.46

Interaction effect

 Cluster 1

Thalamus

R

10

NA

12

−12

6

3.30

 Cluster 2

fusiform

R

38

37

27

−3

−42

−4.07

  1. Hemi hemisphere, L left, R right, BA Brodmann Area, MNI Montreal Neurological Institute, x, y, z, coordinates of primary peak locations in the MNI space, T value statistical value of peak voxel showing ALFF differences among the four groups, PCC posterior cingulated cortex, REC rectus gyrus, mPFC medial prefrontal cortex