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Table 1 Demographic and clinical characteristics of all subjects

From: Exploration of intrinsic brain activity in migraine with and without comorbid depression

  dMIG (n = 10) ndMIG (n = 22) MDD (n = 13) HC (n = 27) P value
Age, y, mean (SD) 27.8 (9.25) 33.59 (8.07) 30.92 (9.1) 29.48 (7,18) 0.206a
Male 3 (30%) 5 (22.7%) 3 (23%) 10 (37%) 0.685b
Education, y, mean (SD) 13.6 (3.41) 19 (3.28) 13.65 (2.93) 16.11 (3.02) 0.531a
Clinical characters of migraine
 With/without aura 0/10 0/22 NA NA  
 Duration of migraine, y, mean (SD) 7.2 (5.55) 9.82 (7.14) NA NA 0.314c
 Attack frequency, per month, mean (SD) 8.52 (7.02) 4.5 (3.50) NA NA 0.08c
 Attack duration, h, mean (SD) 18.65 (14.39) 12.75 (16.79) NA NA 0.42c
 VAS score (0–10), mean (SD) 6.55 (1.17) 5.88 (1.31) NA NA 0.174c
 HIT-6, mean (SD) 65.1 (6.26) 60 (5.77) NA NA 0.081c
 MoCA, mean (SD) 27.5 (2.88) 27.82 (1.5) 27.92 (1.66) 30.59 (1.83) 0.620a
 24-HRSD, mean (SD) 26.9 (6.67) 3 (2.23) 27.85 (6.49) 2.48 (2.12) < 0.001a d
 14-HAMA, mean (SD) 6 (1.826) 3.82 (2.59) 5.23 (2.28) 4.19 (2.69) 0.088a
  1. aP value for the age, MoCA and neuropsychological scores distribution in the four groups were obtained using a separate one-way ANCOVA tests. Post-hoc tests were then performed using the t-test
  2. bP value for the gender distribution and sleep disturbance in the four groups were obtained using a chi-squared test
  3. cP value for the clinical characters distribution for dMIG and ndMIG group were obtained using two sample t-test
  4. dPost-hoc paired comparisons showed significant differences between dMIG versus ndMIG and HC, depression versus ndMIG and HC, P < 0.001
  5. dMIG migraine with depression, ndMIG migraine without depression group, MDD major depressive disorder, HC health control group, VAS visual analogue scale, HIT-6 Headache Impact Test, MoCA Montreal Cognitive Assessment, 24-HRSD 24-Hamilton Rating Scale for Depression, 14-HAMA Hamilton Anxiety Rating Scale Values are represented as the mean (standard deviation)