Fig. 1

Immunohistochemical demonstration of distribution of PACAP and CGRP in the sphenopalatine ganglion (SPG) and the trigeminal ganglion (TG). The figures illustrates that in both ganglia there are cells storing the two neuropeptides and also being alone. The CGRP immunoreactivity occurs more frequent in the TG than does PACAP-ir. Arrows show CGRP positive and PACAP negative cells, while arrow heads show co-localization (above) or negative (below). There are also fibers positive to CGRP. In the SPG the arrow shows a single CGRP positive cell that co-localize PACAP while numerous cells are positive to PACAP only (arrow head). In the right hand SPG illustration  there are several CGRP positive fibers