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Table 6 Studies of SPG blocks for operative pain of the head and face

From: Sphenopalatine ganglion: block, radiofrequency ablation and neurostimulation - a systematic review

Operative Pain of the head and neck

Author

Year

Medical problems

Approach

Imaging

Medication

Number of cases

Study design

Outcome

Robiony et al. [24]

1998

Skeletal transverse discrepancy of the maxilla

Transcutaneous truncal anesthesia of the maxillary nerve in association with transmucosal anesthesia of the sphenopalatine ganglion

None

Prilocaine carbocaine cream

12

Case series

Total anesthesia of the maxillary area facilitated the operations and appreciably reduced amount of postoperative pain

Hwang et al. [23]

2003

Removal of nasal packing after nasal operation

Needle injection into the greater palatine canal

None

1% lidocaine

11

Case-control

Injection side had significantly lower pain than the control side

Ahmed et al. [18]

2007

Endoscopic sinonasal surgery intraoperative isofluorane consumption, hypotensive agents used, postoperative pain

Bilateral SPG block, injected between the middle and inferior turbinates

None

0.5% lidocaine and epinephrine.

15 cases, 15 controls

Randomized-controlled

Significantly reduced intraoperative isofluorane consumption and esmolol use, postoperative tramadol use and postoperative pain.

Ali et al. [20]

2010

Endoscopic trans-nasal resection of pituitary adenoma, anesthetic, vasodilator and analgesic sparing effect

Bilateral SPG block, injected between the middle and inferior turbinates

None

1.5% lidocaine and epinephrine

15 cases and 15 controls

Randomized-controlled

Significantly reduced in sevoflurane and nitroglycerine consumption, emergence time, postoperative pain and need of meperidine analgesia.

Kesimci et al. [22]

2012

Endoscopic sinus surgery postoperative analgesia efficacy

Bilateral SPG block, injected between the middle and inferior turbinates

None

0.5% bupivacaine or 0.5% levobupivacaine

45

Double-blind randomized, placebo-controlled

Postoperative pain significantly reduced, also significantly few patients requiring additional analgesics in the postoperative 24 h.

Demaria et al. [21]

2012

Endoscopic sinus surgery postoperative analgesia efficacy

Bilateral SPG block, palatal approach

None

2% lidocaine and 1% tetracaine

70

Double-blind randomized, placebo-controlled

Patients were discharged sooner than the control group. The block group also required less total fentanyl in the recovery room.

Al-Qudah et al. [19]

2015

Endoscopic sinus surgery postoperative analgesia efficacy

Applied to the SPG region

None

2% lidocaine and epinephrine

60 (30 cases, 30 controls)

Double-blind, placebo controlled

Significant pain reduction in the SPG block group