Skip to main content

Table 13 Studies of SPG radiofrequency ablation on cluster headache

From: Sphenopalatine ganglion: block, radiofrequency ablation and neurostimulation - a systematic review

Cluster headache
First author Year Medical problem Approach Imaging Temperature (°C) Type of RFA Parameter How to identify right spot Study design Number of cases Outcome
Sanders et al. [39] 1997 Cluster headache Infrazygomatic approach Fluoroscopy 70 High frequency 50 Hz, 0.2-1 V Paresthesia in the palate Case-only 66 60.7% of episodic cluster headache patients received complete relief, 30% in chronic cluster headache patients achieved complete relief
Narouze et al. [38] 2009 Chronic cluster headache Infrazygomatic approach Fluoroscopy 80 Unknown 50 Hz at <0.5 V to produce deep paresthesia behind the root of the nose . Prospective cohort 15 Mean attack intensity, mean attack frequency, pain disability index significant reduced at 1 year follow-up (P < 0.0005, P < 0.0003, P < 0.002, respectively)
Chua et al. [78] 2011 Cluster headaches Infrazygomatic approach Fluoroscopy 42 Pulsed 50 Hz, 0.5-0.7 V Paresthesia at the root of the nose Case series 3  Two had excellent relief, one had partial relief by 2 months
Oomen et al. [79] 2012 Atypical facial pain, cluster headache, Sluder’s neuralgia, Sluder’s neuropathy Infrazygomatic approach Fluoroscopy 80 Unknown 50 Hz Paresthesia in the nose and not in the area of the maxillary nerve Case series 3 Adequate pain reduction: 4/4 in atypical facial pain, 2/3 in cluster headache, 1/2 in Sluder’s neuralgia, 2/2 in Sluder’s neuropathy, 1/1 in posttraumatic neuropathy, 0/1 in post-herpetic neuralgia, 0/1 in SUNCT (60% showed considerable pain relief after a single procedure).
Zarembinski et al. [54] 2014 Drug-resistant chronic cluster headache, with Jacob’s disease Initially sphenopalatine ganglion block, then radiofrequency. Fluoroscopy, CT Unknown Unknown Unknown NA Case report 1 Pain significantly improved.
Fang et al. [80] 2015 Cluster headache Infrazygomatic approach CT 42 Pulsed Unknown 0.1-0.3 V to induce paresthesia of the nasal root Case series 16 11 episodic and 1 chronic cluster headache patients had complete relief by 6.3 days. 2 episodic and 2 chronic cluster headache patients had no relief.
Bendersky et al. [81] 2015 Cluster headache Infrazygomatic approach Fluoroscopy 42 Pulsed 45 V, 2 Hz, pulse width 20 ms Paresthesia at the roof of the nose Case series 3 2 patients had no relief, 1 had relief until 1 month. Continue RFA gave relief to all three patients.
Dharmavaram et al. [82] 2016 Cluster headache Lateral approach Fluoroscopy 80 Continuous Unknown paresthesia at the root of the nose was obtained at 0.3 V Case report 1 Pain free for 2 months
Loomba et al. [83] 2016 Cluster headache Infrazygomatic approach CT 80 Continuous 50 Hz <0.3 V to induce paresthesia of the nasal root Case report 1 Near complete resolution at 6 months
\