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Table 5 Estimated magnitudes and habituation in migraineurs in the interictal phase and controls

From: Habituation of laser-evoked potentials by migraine phase: a blinded longitudinal study

 

N1 (μV)

N2P2 (μV)

Pain scores

Coef.

95% CI

Coef.

95% CI

Coef.

95% CI

Main effects

 Migraine

−1.014

[−3.767, 1.739]

−2.395

[−10.707, 5.917]

0.60

[−0.32, 1.52]

 Habituation

−0.374

[−1.527, 0.778]

−5.307***

[−9.232, −1.383]

0.10

[−0.06, 0.26]

Interaction effect

 Migraine × Habituation

−0.268

[−1.875, 1.339]

−0.036

[−4.781, 4.854]

0.13

[−0.09, 0.35]

Constant

7.365

[5.070, 9.660]

39.382

[33.531, 45.234]

3.54

[3.01, 4.07]

  1. The constant represents first-block amplitude or pain score responses in controls. The main effect of migraine represents the first-block amplitude or pain score difference between groups. The main effect of habituation represents the difference between first and second block amplitudes, or linear change in pain scores, in the control group. The interaction effect represents the habituation-difference between groups. Thus, the significant coefficient is interpreted as N2P2 habituation in the control group. The corresponding interaction effect is not significant, indicating no difference in habituation between controls and migraineurs in the interictal phase. Random effects estimates are shown in Supplementary Table 3. * p < 0.05, ** p < 0.01, *** p < 0.001