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Table 3 Onabotulinumtoxin A (OBT-A) in the context of other prophylactic therapies for chronic migraine and timing of OBT-A initiation

From: Onabotulinumtoxin A for the management of chronic migraine in current clinical practice: results of a survey of sixty-three Italian headache centers

Answer options

n (%)

Frequency of combination of OBT-A with other prophylactic therapies

 Never

3 (4.8)

 Rarely

14 (22.2)

 Frequently

45 (71.4)

 Always

1 (1.6)

Number of prophylactic therapies used before initiating OBT-A

 0

1 (1.6)

 1

2 (3.2)

 2-3

22 (34.9)

 > 3

38 (60.3)

Rating of tolerability profile of OBT-A vs. oral prophylactic therapies

 More favorable

57 (90.5)

 Comparable

5 (7.9)

 Less favorable

1 (1.6)

Rating of efficacy/safety ratio of OBT-A vs. oral prophylactic therapies

 More favorable

44 (69.8)

 Comparable

18 (28.6)

 Less favorable

1 (1.6)

Impression of greater efficacy of OBT-A when initiated early in the course of chronic migraine

 Never

0

 Rarely

9 (14.3)

 Frequently

51 (80.9)

 Always

3 (4.8)

Recommendation of OBT-A as first-line treatment based on the pharmacological profile

 Yes

30 (47.6)

 No

33 (52.4)