Fig. 3From: Differential inhibitory response to telcagepant on αCGRP induced vasorelaxation and intracellular Ca2+ levels in the perfused and non-perfused isolated rat middle cerebral arteryCross-sections of middle cerebral arteries showing CLR and RAMP1 expression in the smooth muscle cells of the MCA walls. Both receptor antibodies revealed positive staining in the smooth muscle cell layer. A 50 μm marker is inserted. Figure 3a and d demonstrates the expression of CLR and RAMP1 in the smooth muscle cells of the MCA walls. DAPI, a nucleus stain has been added to picture 3b and e. 3c and e are negative controls where the fluorescence staining around the lumen is due to autofluorescence of the lamina elastica internaBack to article page