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Fig. 2 | The Journal of Headache and Pain

Fig. 2

From: Pharmacological analysis of the increases in heart rate and diastolic blood pressure produced by (S)-isometheptene and (R)-isometheptene in pithed rats

Fig. 2

Effects of i.v. bolus injections of: (a) saline; (b) prazosin (Praz); (c) rauwolscine (Rauw); (d) the combination of Praz plus Rauw; or (e) propranolol (Prop) on the increases in heart rate (∆ Heart rate) produced by (S)-isometheptene (0.03-3 mg/kg, i.v.) in pithed rats. *P < 0.05 vs. the corresponding dose in the control curve; # P < 0.05 vs. the corresponding dose in the curve obtained after saline; n = 5 for each group

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