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Fig. 1 | The Journal of Headache and Pain

Fig. 1

From: Pharmacological analysis of the increases in heart rate and diastolic blood pressure produced by (S)-isometheptene and (R)-isometheptene in pithed rats

Fig. 1

Effects of i.v. bolus injections of isometheptene enantiomers (0.03-3 mg/kg) or saline (1 ml/kg, given 5 times) on (a) heart rate; and (b) diastolic blood pressure (DBP) in pithed rats. Full symbols represent significant differences (P < 0.05) vs saline (vehicle). *P < 0.05 vs. the corresponding dose to (R)-isometheptene; n = 6 for each group

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