Fig. 4

Forest plot of the meta-analysis showed a significant decrease in the numbers of monthly migraine days after therapy with CGRP-mAbs compared with placebo from baseline to weeks 1–4, 5–8, and 9–12. a The numbers of monthly migraine days of CGRP-mAbs and placebo at weeks 1–4; b The numbers of monthly migraine days of CGRP-mAbs and placebo at weeks 5–8; c The numbers of monthly migraine days of CGRP-mAbs and placebo at weeks 9–12. CGRP-mAbs, monoclonal antibodies to CGRP and its receptor; IV, inverse variance; CI, confidence interval