From: The potential impact of primary headache disorders on stroke risk
Variable | PHDs cohort | Comparison cohort | Adjusted HR (95% CI) | ||||
---|---|---|---|---|---|---|---|
Event | PYs | Rate | Event | PYs | Rate | ||
All strokes | 100 | 6,149 | 162.62 | 287 | 24,742 | 116.00 | 1.40 (1.13–1.68)** |
 Haemorrhagic | 4 | 6,149 | 6.50 | 30 | 24,742 | 12.12 | 0.55 (0.25–1.58) |
 Ischaemic | 96 | 6,149 | 156.11 | 257 | 24,742 | 103.87 | 1.49 (1.15–1.98)** |
<45 years | |||||||
All strokes | 13 | 2,951 | 44.05 | 33 | 12,539 | 26.32 | 1.66 (0.79–2.97) |
 Haemorrhagic | 1 | 2,951 | 3.39 | 7 | 12,539 | 5.58 | 0.63 (0.10–4.00) |
 Ischaemic | 12 | 2,951 | 40.66 | 26 | 12,539 | 20.73 | 1.95 (0.97–3.74) |
45–64 years | |||||||
All strokes | 50 | 2,568 | 194.73 | 124 | 9,222 | 134.46 | 1.43 (1.03–2.00)* |
 Haemorrhagic | 3 | 2,568 | 11.68 | 13 | 9,222 | 14.10 | 0.81 (0.15–2.77) |
 Ischaemic | 47 | 2,568 | 183.04 | 111 | 9,222 | 120.36 | 1.50 (1.11–2.10)* |
≧65 years | |||||||
All strokes | 37 | 631 | 586.68 | 130 | 2,981 | 436.14 | 1.33 (0.91–1.91) |
 Haemorrhagic | 0 | 631 | 0 | 10 | 2,981 | 33.55 | 0 |
 Ischaemic | 37 | 631 | 586.68 | 120 | 2,981 | 402.59 | 1.42 (0.99–2.08) |
Male | |||||||
All strokes | 35 | 1,730 | 202.36 | 101 | 6,918 | 146.00 | 1.37 (0.91–2.02) |
 Haemorrhagic | 3 | 1,730 | 17.35 | 15 | 6,918 | 21.68 | 0.80 (0.25–2.70) |
 Ischaemic | 32 | 1,730 | 185.02 | 86 | 6,918 | 124.32 | 1.46 (0.91–2.10) |
Female | |||||||
All strokes | 65 | 4,420 | 147.06 | 186 | 17,825 | 104.35 | 1.40 (1.04–1.80)* |
 Haemorrhagic | 1 | 4,420 | 2.26 | 15 | 17,825 | 8.42 | 0.26 (0.02–2.00) |
 Ischaemic | 64 | 4,420 | 144.80 | 171 | 17,825 | 95.93 | 1.49 (1.13–1.90)** |