Prevalence of restless legs syndrome in migraine patients with and without aura: a cross-sectional, case-controlled study

Table 2 Comparison of RLS prevalence across study groups

Population/RLS	No migraine controls (N = 133)	Episodic migraine groups			p value^†	p value^§
Population/RLS	No migraine controls (N = 133)	1–8 days (N = 224)	9–14 days (N = 91)	≥15 days (N = 57)	p value^†	p value^§
Whole cohort (N = 505)					0.026	0.256
Non-RLS	128 (96.2)	213 (95.1)	85 (93.4)	50 (87.7)
RLS	5 (3.8)	11 (4.9)	6 (6.6)	7 (12.3)
With aura (N = 244)					0.002	0.043
Non-RLS	128 (96.2)	66 (93.0)	20 (87.0)	13 (76.5)
RLS	5 (3.8)	5 (7.0)	3 (13.0)	4 (23.5)
Without aura (N = 394)					0.385	0.750
Non-RLS	128 (96.2)	147 (96.1)	65 (95.6)	37 (92.5)
RLS	5 (3.8)	6 (3.9)	3 (4.4)	3 (7.5)

^†Linear trend analysis by Cochran–Armitage chi-square test (unadjusted analysis);
^§Linear contrast in the multivariable logistic regression with adjustment of gender, age, body mass index, education level, smoking status, alcohol consumption, coffee consumption, HADS anxiety, HADS depression, and PSQI score

ISSN: 1129-2377