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Table 5 Headache related disability, affect and quality of life scores following occipital nerve stimulation

From: Long-term outcomes of occipital nerve stimulation for chronic migraine: a cohort of 53 patients

  Pre ONS (n = 53) Post ONS (n = 53) Mean Change in Score (95 % CI) p-value
Whole cohort (n = 53)
 MIDAS     0.188
  Mean (±SD) 154.91 (±84.03) 134.28 (±92.70) 20.62
  Range 18–270 0–270 (−10.41, 51.65)
 HIT-6     0.009*
  Mean (±SD) 69.17 (±6.88) 65.23 (±9.27) 3.94
  Range 52–98 36–89 (1.04, 6.84)
 HAD-A     0.618
  Mean (±SD) 10.34 (±4.46) 9.96 (±4.86) 0.377
  Range 2–21 0–19 (−1.13, 1.88)
 HAD-D     0.127
  Mean (±SD) 11.36 (±4.23) 10.26 (±5.40) 1.09
  Range 1–20 0–20 (−0.32, 2.51)
 BDI-II     0.132
  Mean (±SD) 26.11 (±11.07) 23.13 (±13.59) 2.98
  Range 2–46 0–59 (−0.93, 6.89)
 SF-36 Physical Composite     0.054
  Mean (±SD) 27.12 (±8.16) 29.41 (±11.43) −2.29
  Range 11.1–15.9 12.1–55.7 (−4.62–0.04)
 SF-36 Mental Composite     0.076
  Mean (±SD) 34.72 (±11.54) 37.97 (±13.25) −3.25
  Range 19.6–62.5 9.8–61.2 (−6.84–0.35)
 EQ5D     
  Mean (±SD) 0.66 (±0.11) 0.64 (±0.15) 0.02 0.317
  Range 0.26–0.83 0.25–1.0 (−0.16–0.05)
 EQ-VAS     
  Mean (±SD) 40.51 (±21.09) 49.78 (±25.00) 9.27 0.009*
  Range 0–90 5–95 (−16.09– −2.43)
Chronic migraine alone (n = 35)
 MIDAS     
  Mean (±SD) 162.17 (±86.50) 135.97 (±91.33) 26.20 0.194
  Range 18–270 0–270 (−13.95,66.35)
 HIT-6     
  Mean (±SD) 69.91 (±6.72) 66.26 (±8.14) 3.65 0.038*
  Range 61–98 36–78 (0.21, 7.10)
 HAD-A     
  Mean (±SD) 10.69 (±4.33) 10.83 (±4.42) −0.14 0.864
  Range 2–21 2–18 (−1.82, 7.10)
 HAD-D     
  Mean (±SD) 11.91 (±4.09) 11.34 (±5.01) 0.57 0.396
  Range 3–20 1–19 (−0.78, 1.92)
 BDI-II     
  Mean (±SD) 27.09 (±11.22) 24.37 (±13.03) 2.71 0.199
  Range 2–45 0–48 (−1.49, 6.92)
 SF-36 Physical Composite     
  Mean (±SD) 27.71 (±8.11) 27.69 (±10.58) 0.02 0.986
  Range 11.10–45.90 12.10–55.0 (−2.6, 2.73)
 SF-36 Mental Composite     
  Mean (±SD) 32.71 (±11.20) 36.86 (±12.72) −4.14 0.039*
  Range 19.60–62.50 9.80–61.20 (−80.7, −0.22)
 EQ5D     
  Mean (±SD) 0.56 (±0.12) 0.62 (±0.15) 0.03 0.105
  Range 0.26–0.83 0.25–0.83 (−0.01, 0.07)
 EQ-VAS     
  Mean (±SD) 42.43 (±22.44) 48.64 (±22.87) −6.21 0.057
  Range 10–90 10–90 (−12.63, 0.20)
Multiple phenotypes (n = 18)
 MIDAS     
  Mean (±SD) 140.78 (±79.46) 131.00 (±97.89) 9.77 0.701
  Range 24–270 0 + 270 (−42.96, 62.52)
 HIT-6     
  Mean (±SD) 67.72 (±7.16) 63.22 (±11.14) 4.50 0.122
  Range 52–78 42–89 (−1.33, 10.33)
 HAD-A     
  Mean (±SD) 9.67 (±4.75) 8.28 (±5.36) 1.38 0.377
  Range 3–18 0–19 (−1.84, 4.62)
 HAD-D     
  Mean (±SD) 10.44 (±4.69) 8.17 (±5.63) 2.27 0.178
  Range 1–19 0–20 (−1.14, 5.69)
 BDI-II     
  Mean (±SD) 24.22 (±10.85) 20.72 (±14.68) 3.50 0.415
  Range 6–46 0–59 (−5.33, 12.33)
 SF-36 Physical Composite     
  Mean (±SD) 26.85 (±7.59) 36.36 (±12.55) −5.91 0.010*
  Range 13.70–42.50 12.70–55.70 (−10.23, −1.58)
 SF-36 Mental Composite     
  Mean (±SD) 36.36 (±11.24) 40.13 (±14.35) −3.77 0.329
  Range 20.10–59.40 15.30–59.50 (−11.68, 4.14)
 EQ5D     
  Mean (±SD) 0.65 (±0.85) 0.67 (±0.13) −0.14 0.619
  Range 0.54–0.83 0.41–1.00 (−0.77, 0.04)
 EQ-VAS     
  Mean (±SD) 37.35 (±18.88) 51.65 (±28.81) −14.29 0.069
  Range 10–70 5–95 (−29.85, 1.26)
  1. BDI-II, Becks Depression Inventory; CI, confidence interval; EQ-VAS, Euro-QoL visual analogue score; EQ5D, Euro-QoL 5D Index; HAD-A, Hospital Anxiety and Depression scores-anxiety specific; HAD-D, Hospital Anxiety and Depression scores – depression specific; HIT-6, Headache Impact Test; MIDAS, Migraine Disability Assessment Scale; ONS, occipital nerve stimulation; SD (Standard deviation); SF-36, Short Form 36