Table 1 Baseline characteristics of included RCTs
Author | No. of patients | Mean age (year) | Mean duration before treatment (year) | Frequency of attacks per day before treatment (SD) | Pain severity before treatment, VAS Mean (SD) | Mean follow up (week) | Mean duration of effect (week) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
cases | control | cases | control | cases | control | cases | control | cases | control | cases | control | cases | control | ||||
Zhang et al. [24] | 25 Group1: 25U | 28 Group2: 75U | 27 | 58.16 | 62.64 | 58.41 | ND | ND | ND | ND | 6.24 (2.13) | 7.18 (2.21) | 6.96 (1.97) | ND | ND | ND | ND |
Shehata et al. [26] | 10 | 10 | ND | ND | ND | ND | 36.7 (3.13) | 39.2 (3.05) | 8.3 | 8.5 | 12 | 12 | ND | ND | |||
Wu et al. [23] | 20 | 22 | 59.14 | 58 | ND | ND | 21.71 (22.68) | 20.53 (10.38) | 7.05 (2.03) | 6.88 (2.25) | 12 | 12 | 12 | 12 | |||
Zúñiga et al. [25] | 16 | 20 | 64.5 | 66.06 | 6.2 | 5.2 | 29.1 (31.36) | 31.06 (31.62) | 8.85 | 8.19 | 8 | 8 | 8 | 8 | |||