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Table 1 Effects of topical applications of anandamide and NADA on meningeal blood flow

From: Endovanilloids are potential activators of the trigeminovascular nocisensor complex

 

Concentration

Changes in blood flow (%)

Number

p-value

Anandamide

100 nM

3.4 ± 1.5

8

0.06

 

1 μM

2.5 ± 1*

10

0.033

 

10 μM

−2.1 ± 0.8*

10

0.022

NADA

10 nM

7.4 ± 2*

10

0.003

 

100 nM

24 ± 4.7*

11

0.016

 

1 μM

−7.7 ± 4.3

6

0.09

  1. *: Statistically different from the baseline (p < 0.05)