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Fig. 2 | The Journal of Headache and Pain

Fig. 2

From: Endovanilloids are potential activators of the trigeminovascular nocisensor complex

Fig. 2

Effect of AM 251 and CGRP8–37 on anandamide-induced vasodilatation in the dura mater. Original recording (a) and statistical evaluation (b) of changes induced by anandamide (10 μM) before and after the application of AM 251 (100 μM) or AM 251 (100 μM) and CGRP8–37 (100 μM). Percentage changes in blood flow were calculated as mean ± SEM for the 3-min application period relative to the baseline. The number of experiments is indicated in the bars. *: statistically different from the effect of anandamide after AM 251 pretreatment (p < 0.05)

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