Fig. 6

Magnetic source imaging (MSI) showing the locations of neuromagnetic activation in response to left-finger movement in a representative chronic migraine subject, acute migraine subject, and control subject. The primary motor cortex in the hemisphere contralateral to the finger pressing the button is activated in all the three subjects (no arrows). The ipsilateral sensorimotor area, supplementary motor area, and the pre-motor areas are activated only in chronic and acute migraine subjects (green arrows). The deep brain area is activated only in the chronic migraine subject (cyan arrows). In all coronal and axial views, “R” indicates right and “L” indicates left. Below the MSI images are bar graphs indicating the sources of neuromagnetic activation elicited by left finger movements in three groups of subjects. The bars show the number of subjects having activation in each location in each group. M1 indicates primary motor area; IMA indicates ipsilateral motor area; PMA indicates pre-motor area; SMA indicates supplementary motor area; OCA incites occipital area and DBA indicates deep brain area. The odds ratio was statistically analyzed by comparing each group. The double asterisk indicates p < 0.001; and a single asterisk indicates p < 0.01. A red asterisk indicates a difference between acute and chronic migraines and blue asterisks represent the other group differences