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Table 4 Base casea cost-effectiveness analysis

From: Cost-effectiveness analysis of non-invasive vagus nerve stimulation for the treatment of chronic cluster headache

Treatment group Mean cost, € Mean QALY ICERb
nVNS + SoC 7096.96 0.607 nVNS dominant over SoCc
SoC alone 7511.35 0.522
  1. Abbreviations: ICER incremental cost-effectiveness ratio, nVNS non-invasive vagus nerve stimulation, QALY quality-adjusted life-year, SoC standard of care
  2. Probabilistic estimates are based on mean results across all Monte Carlo simulations [21]
  3. aIn the base case, subjects in the nVNS + SoC group who responded through the extension phase were assumed to maintain response
  4. bThe expense of gaining an additional QALY with adjunctive nVNS therapy (vs SoC alone)
  5. cIndicates that adjunctive nVNS therapy was more effective and cost saving than SoC alone