Table 1 Effects of a single NTG migraine episode on behavioral endpoints
From: Clinically relevant behavioral endpoints in a recurrent nitroglycerin migraine model in rats
Endpoints | Saline | NTG |
|---|---|---|
Grimace Score (60-90-120 m) | .057/.025/.063 (.096/.053/.106) | .163/.207/.188 (.289/.379/.319) |
Cool-Tailflick Latency (s) | 16.8 (10.0) | 19.2 (13.6) |
Warm-Tailflick Latency (s) | 8.9 (6.2) | 12.3 (5.7) |
Time in Light Box (s) | 27.2 (12.7) | 40.4 (19.6) |
Locomotor Activity (# beam breaks) | 105.8 (29.0) | 217.8* (79.4) |