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Table 3 Distributions of the T21M and S89N polymorphisms among the groups

From: Plasma urotensin-2 level and Thr21Met but not Ser89Asn polymorphisms of the urotensin-2 gene are associated with migraines

Genotype/Allele

Control (n = 171) n (%)

Migraine (n = 186) n (%)

p

OR [95 % CI]

T21M

 TT

72 (42.1)

64 (34.4)

Reference

 

 TM

69 (40.4)

100 (53.8)

0.035

1.63 [1.034–2.571]

 MM

30 (17.5)

22 (11.8)

0.559

0.825 [0.433–1.572]

 T

213 (62.3)

228 (61.3)

Reference

 

 M

129 (37.7)

144 (38.7)

0.786

1.043 [0.771–1.411]

 HWE

p = 0.065

p = 0.069

  

S89N

 SS

151 (88.3)

161 (86.6)

Reference

 

 SN

20 (11.7)

25 (13.4)

0.620

1.172 [0.625–2.198]

 NN

0 (0.0)

0 (0.0)

-

 S

322 (94.2)

347 (93.3)

0.632

0.862 [0.470–1.582]

 N

20 (5.8)

25 (6.7)

Reference

 

 HWE

p =0.417

p =0.325

  
  1. OR odds ratio, CI confidence interval, and HWE Hardy Weinberg equilibrium
  2. *p < 0.05