Table 3 MOH sub-diagnosis in relation to primary headache diagnosis
Primary headache diagnosis | Acute analgesics | Denmark | Germany | Italy | Spain | Argentina | Chile | Europe | Latin America | P-value | Total |
|---|---|---|---|---|---|---|---|---|---|---|---|
N | 38 | 81 | 97 | 43 | 91 | 86 | 259 | 177 | 436 | ||
Migraine | Ergotamines | 5.3 | 1.2 | 4.1 | 2.3 | 81.3 | 62.8 | 3.1 | 72.3 | <0.001* | 31.2 |
Triptans | 55.3 | 37.0 | 47.4 | 16.3 | 4.4 | 8.1 | 40.2 | 6.2 | <0.001* | 26.4 | |
Simple analgesics | 26.3 | 60.5 | 29.9 | 79.1 | 26.4 | 34.9 | 47.1 | 30.5 | 0.001* | 40.4 | |
Opioids | 5.3 | 6.2 | 0.0 | 0.0 | 0.0 | 0.0 | 2.7 | 0.0 | 0.045 | 1.6 | |
Combination-analgesics | 18.4 | 21.0 | 21.6 | 4.7 | 3.3 | 62.8 | 18.1 | 32.2 | 0.001* | 23.9 | |
Poly-overuse | 5.3 | 2.5 | 3.1 | 4.7 | 0.0 | 1.2 | 3.5 | 0.6 | 0.54 | 2.3 | |
N | 33 | 2 | 1 | 15 | 7 | 2 | 51 | 9 | 60 | ||
TTH | Ergotamines | 0.0 | 0.0 | 0.0 | 6.7 | 100.0 | 100.0 | 2.0 | 100.0 | <0.001* | 16.7 |
Triptans | 0.0 | 0.0 | 0.0 | 6.7 | 0.0 | 0.0 | 2.0 | 0.0 | 1.00 | 1.7 | |
Simple analgesics | 81.8 | 50.0 | 100.0 | 86.7 | 42.9 | 0.0 | 82.4 | 33.3 | 0.005 | 75.0 | |
Opioids | 3.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 2.0 | 0.0 | 1.00 | 1.7 | |
Combination-analgesics | 36.4 | 100.0 | 0.0 | 13.3 | 0.0 | 50.0 | 31.4 | 11.1 | 0.42 | 28.3 | |
Poly-overuse | 3.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 2.0 | 0.0 | 1.00 | 1.7 | |
N | 54 | 18 | 19 | 34 | 28 | 20 | 125 | 48 | 173 | ||
Migraine and TTH | Ergotamines | 3.7 | 0.0 | 0.0 | 14.7 | 14.3 | 40.0 | 5.6 | 66.7 | <0.001* | 22.5 |
Triptans | 33.3 | 22.2 | 15.8 | 11.8 | 3.6 | 5.0 | 23.2 | 4.2 | 0.003* | 17.9 | |
Simple analgesics | 38.9 | 66.7 | 63.2 | 79.4 | 35.7 | 55.0 | 57.6 | 43.8 | 0.13 | 53.8 | |
Opioids | 3.7 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 1.6 | 0.0 | 1.00 | 1.2 | |
Combination-analgesics | 51.9 | 22.2 | 21.1 | 11.8 | 3.6 | 45.0 | 32.0 | 20.8 | 0.19 | 28.9 | |
Poly-overuse | 1.9 | 0.0 | 10.5 | 2.9 | 0.0 | 0.0 | 3.2 | 0.0 | 0.58 | 2.3 |