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Table 5 Probability of reporting interictal burden according to measures of ictal burden in participants with migraine

From: Interictal burden attributable to episodic headache: findings from the Eurolight project

Ictal burden measure

Probability of reporting interictal burden

Odds ratio [95 % CI]

Interictal anxiety

Interictal avoidance

Not free of all symptoms

Headache intensity (reference: “not bad”)

“bad”

2.8 [1.5–5.4]

1.6 [1.1–2.4]

1.1 [0.8–1.4]

“very bad”

7.6 [4.0–14.7]

3.0 [2.0–4.6]

1.3 [1.0–1.8]

Headache frequency (days/year) (reference: ≤12)

13–24

2.4 [1.5–3.7]

1.6 [1.1–2.2]

1.1 [0.8–1.4]

25–48

2.5 [1.7–3.8]

2.0 [1.5–2.8]

1.3 [1.0–1.6]

49–90

3.7 [2.5–5.6]

2.7 [1.9–3.6]

1.3 [1.0–1.6]

>90

6.4 [4.3–9.6]

2.5 [1.8–3.6]

1.8 [1.3–2.3]

In control of headaches (reference: “always”)

“often”

1.1 [0.7–1.9]

1.5 [1.0–2.2]

1.1 [1.1–1.9]

“sometimes”

3.5 [2.1–5.6]

2.8 [1.9–4.1]

1.9 [1.4–2.5]

“rarely” or “never”

4.1 [2.5–6.9]

2.6 [1.7–3.9]

2.5 [1.8–3.4]

Lost productive time (HALT index): lost work time (days/3 months) (reference: ≤11)

12–22

5.3 [3.6–7.9]

2.9 [1.9–4.3]

1.8 [1.2–2.6]

23–33

4.2 [2.0–8.9]

2.3 [1.1–5.0]

1.8 [0.9–3.7]

>33

4.2 [1.7–10.2]

2.7 [1.1–6.6]

1.9 [0.8–4.4]

lost household time (days/3 months) (reference: ≤11)

12–22

2.4 [1.7–3.6]

2.4 [1.7–3.4]

1.3 [0.9–1.8]

23–33

3.6 [2.1–6.3]

2.3 [1.3–4.0]

1.8 [1.1–3.0]

>33

5.3 [2.6–10.7]

3.8 [1.9–7.6]

1.7 [0.9–3.5]

lost work + household time + social events (days/3 months) (reference: ≤22)

23–44

4.1 [2.9–5.7]

2.9 [2.1–4.0]

1.5 [1.1–2.0]

45–66

4.0 [2.2–7.2]

2.8 [1.6–5.0]

2.2 [1.3–3.6]

>66

4.4 [2.3–8.3]

2.4 [1.3–4.5]

1.7 [1.0–3.1]