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Table 2 Genotype frequencies of gene polymorphism in Chinese population

From: Case-control study of GRIA1 and GRIA3 gene variants in migraine

Gene

SNP

Group

 

Genotype n(%)

P

GRIA1

rs548294

 

GG

GA

AA

 

Migraine

159(48.0)

130(39.3)

42(12.7)

.642

MA

28(59.6)

16(34.0)

3(6.4)

.280

MO

131(46.1)

114(40.1)

39(13.7)

.494

Control

157(47.6)

138(41.8)

35(10.6)

 

rs2195450

 

CC

CT

TT

 

Migraine

238(71.9)

81(24.5)

12(3.6)

.004*

MA

31(66.0)

15(31.9)

1(2.1)

.027

MO

207(72.9)

66(23.2)

11(3.9)

.011**

Control

272(82.4)

53(16.1)

5(1.5)

 

GRIA3

rs3761555

 

GG

GA

AA

 

Migraine

135(40.8)

154(46.5)

42(12.7)

.564

MA

21(44.7)

19(40.4)

7(14.9)

.864

MO

114(40.1)

135(47.5)

35(12.3)

.470

Control

134(40.6)

145(43.9)

51(15.5)

 
  1. Abbreviations: MA migraine with aura, MO migraine without aura, SNP single nucleotide polymorphisms
  2. *All female migraine patients compared with controls by genotype: P < .017
  3. **MO compared with controls by genotype: P < .017